Instruct-NL > Bijvoet Center - UU

The Bijvoet Center for Biomolecular Research at Utrecht University studies the relation between the structure and function of biomolecules.

Bijvoet Center - UU

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Solid state NMR, Utrecht, Netherlands

The Bijvoet Center houses solid state 950, 800, 700, 500 and 400 MHz NMR equipment for the characterization of biomolecules, their structure determination and dynamical and functional studies. All of the NMR instruments are state-of-the-art digital Bruker NMR spectrometers. In addition to the standard pulse sequences for spectroscopic, structural, dynamical, and functional characterization, tailored pulse sequences for structural determination of high molecular weight proteins and other special applications such as in-cell NMR experiments are developed and available. Dynamic Nuclear Polarization (DNP) capabilities on the 800 and 400 MHz instruments provide a significant boost in sensitivity.

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Bijvoet Center - UU

The Bijvoet Center for Biomolecular Research is part of the Instruct-NL national Instruct Centre in the Netherlands and has facilities for high-throughput mass spectrometry on proteins and peptides, X-ray crystal structure determination of biomolecules as well as small molecules and high-field NMR instrumentation for both liquid- and solid-phase NMR analysis of proteins.

The Bijvoet Center currently offers access to native protein mass spectrometry, which allows determination of protein mass, complex stoichiometry, and, in combination with ion mobility separation, overall characterization of the structure of protein complexes, to both liquid- and solid-phase NMR (primarily through iNEXT) to enable structure determination of biomolecules and/or the characterization of their macromolecular complexes.


In Instruct, access is also especially offered to integrated projects, using multiple technologies, either at the Bijvoet Center, or in collaboration with on of the other Instruct Centres.

Important: to ensure a smooth application process, we strongly recommend any users to contact us before submitting an application.

Visit This Centre

The Bijvoet Center is located at Utrecht Science Park "De Uithof" in Utrecht, the Netherlands. Please see the institute website for detailed contact information.

Publications

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Visit this centre and more by submitting a proposal for access.

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Scientific Contacts

  • Marc Baldus login to contact
  • Rolf Boelens login to contact
  • Alexandre Bonvin login to contact
  • Piet Gros login to contact
  • Albert Heck login to contact

Admin Contacts

  • Reinout Raijmakers login to contact

Technical Contacts

  • Bijvoet Center login to contact
  • Hans Wienk login to contact
  • Hans Wienk login to contact