THREE Wellcome Trust funded postdoctoral fellowships are available in Peijun Zhang lab at the University of Oxford.
1) Structural mechanisms of HIV-1 restriction by capsid-sensing host proteins
2) Correlative cryo super-resolution fluorescence microscopy and cryoET of HIV-1 and host interactions
3) Structural mechanism of HIV-1 inhibition by SERINCs
Zhang lab combines structural methodologies, in particular cryoEM and cryoET, with biochemistry and functional studies, in conjunction with molecular-dynamics simulations, to gain new insights into the mechanisms of HIV-1 inhibition by host cell factors. The Division of Structural Biology in Oxford has excellent facilities for molecular and cellular cryoEM/ET and state-of-the-art cryo-fluorescence microscopy and high performance computing. They are also closely connected to the UK national cryoEM center, eBIC at the Diamond Light Source.
Candidates must be highly motivated, hold a PhD in biophysics/structural biology or equivalent, and have a demonstrated track record in conducting high quality original research. Knowledge in cryoEM/ET and protein biochemistry, and experience in structural biology (posts 1&3), or live-cell fluorescence microscopy (posts 2&3) are essential.
Online applications are open (closing date: 07-Aug-2017)
Postdoctoral Research Fellow in HIV-host interactions
Postdoctoral Research Fellow in Correlative Microscopy
Postdoctoral Research Scientist in STRUBI
For further details, please contact Peijun Zhang at peijun@strubi.ox.ac.uk
