Instruct Biennial Meeting

20th-22nd May 2015

Florence, Italy

Showcasing Integrative Structural Biology

The second Instruct Biennial Structural Biology Meeting at Convitto Della Calza, Florence, Italy 20-22 May 2015 will showcase integrative structural biology and its impact on biological research. The program will include sessions that represent recent advances on structural biology toward cellular biology, emerging methods and technologies and results of biomedical importance. Confirmed speakers are: John Womersley (ESFRI, STFC), Wah Chiu (Baylor), Patrick Cramer (Ludwig-Maximilians-Universität München), Marc Baldus (Utrecht University), Teresa Carlomagno (EMBL Heidelberg), Sriram Subramaniam (NIH), Eddy Arnold (Rutgers), Helena Käck (Astrazeneca) and Anne-Claude Gavin (EMBL). A session will focus on Instruct in the wider context of integrated European infrastructures. Eero Vuorio, Director of Biocenter Finland (BBMRI) and David Stuart (Instruct director, University of Oxford) have confirmed their participation to speak in this session. Young scientists who want to know where structural biology is and where it is going are especially encouraged to attend.

Organising Committee

About the Conference

The Instruct Council requested a biennial meeting to showcase Instruct's role in developing integrative structural biology and its impact on biological research starting in 2013, Heidelburg and now continues again in 2015, Florence. The meetings bring together exciting developments in structural biology in Europe as well as international speakers.

The meetings also aim to help the integration of Instruct with other European infrastructure projects in the biomedical area as well as industrial partners.

Venue Information


The 2015 Instruct Biennial Structural Biology Meeting will be held at Convitto Della Calza.

Conference Center, art, culture, tradition and hotel hospitality, are the distinguishing features of Convitto della Calza, located in the heart of the city, unique among Florence hotels for its combination of a 16th-century cloister and halls frescoed with masterpieces such as Francibigio's Last Supper, with very modern meeting rooms and hospitality in a charming location.

At the entrance to Florence, in the characteristic quarter of Oltrarno very close to the Boboli Garden, Pitti Palace and the Ponte Vecchio, the Hotel Convitto della Calza with its prestigious conference center, is located in a truly strategic position: easily reached from both the tollway and the Santa Maria Novella train station.

From the Santa Maria Novella train station (which is also the terminal for the Florence Airport shuttle) it takes only a few minutes by bus ,while groups arriving to Florence by motor coach will find a comfortable area for loading and unloading right in front of the hotel.

Near-by Accommodation

The following hotel has been arranged at discounted rates if booked before the 31st January 2014. Please complete the following form and email to Rachele Taddeucci at the venue to book at the discounted rate:

biennial-hotel1 Hotel Villa Carlotta ()
Via Michele di Lando 3

The following hotels are within 10/15 minutes walking distance from the venue:

biennial-hotel1 Hotel Villa Betania ()
Via del Poggio Imperiale 23

biennial-hotel1 Pitti Palace Hotel ()
Via Borgo San Jacopo 3r

biennial-hotel1 Hotel La Scaletta ()
Via Guicciardini 13

The following hotels are within 20/25 minutes walking distance from the venue:

biennial-hotel1 L’O Hotel L’Orologio ()
P.zza Santa MARIA Novella 24

biennial-hotel1 Unicorno ()
Via dei Fossi 27

Elite ()
Via della Scala 12

Day 1 - 20th May

Session 1 "Structural biology towards Cellular Biology: Integrating Biology"


(Chair: Lucia Banci and David Stuart)

09:00-09:25Patrick Cramer
Max Planck Institute Göttingen
09:30-09:55Marc Baldus
Utrecht University
10:00-10:25Anastassis Perrakis
NKI Netherlands
11:00-11:25Chiara Zucchelli
S. Raffaele Scientific Institute
11:30-11:55Teresa Carlomagno
EMBL Heidelberg
12:00-12:10Presentation of the Ivano Bertini award by Instruct and Bruker
12:10-12:35Ivano Bertini Award Talk: Stephen Cusack
EMBL Grenoble

Session 2 "Structural Biology and Health: Current Challenges"


(Chair: Maria Arménia Carrondo and Gunter Schneider)

14:00-14:25Matthew Bottomley
14:30-14:55Sriram Subramaniam
15:00-15:25Eddy Arnold
16:00-16:25Nehar Mortuza
University of Copenhagen
16:30-16:55Helena Käck

Poster session and drinks


Instruct Centres, studentships and selected attendees will exhibit within the poster session.

Day 2 - 21st May

Session 3 "Emerging Technologies in Integrative Structural Biology"


(Chair: Jose Maria Carazo and Eva Pebay-Peyroula)

09:00-09:25Christos Savva
09:30-09:55Christiane Ritter
10:00-10:25Anne-Claude Gavin
11:00-11:25Areej Abuhammad
11:30-11:55Jan Steyaert
12:00-12:25Imre Berger

Session 4 "The joint activities and impact of European Biomedical Infrastructures"


(Chairs: Eero Vuorio and Alberto Podjarny)

14:00-14:25Dave Stuart
14:30-14:55Esko Oksanen
15:30-15:55Giovanni Migliaccio
16:00-16:25John Womersley
16:30-16:55Eero Vuorio
Biocenter Finland and BBMRI

Close of scientific meeting

Day 3 - 22nd May

Instruct Internal Executive Meeting


Instruct Internal Council Meeting


Ivano Bertini Award

A biennial award has been set up in memory of Ivano Bertini, who pioneered innovative methodologies in the field of NMR and championed technology integration as a foundation for correlative structural biology. The award recognises scientists who have undertaken frontier research utilising an integrative structural biology approach which aligns with the Instruct vision.

Nominations are invited for the Ivano Bertini Award 2015 for a significant achievement in any area of the biological sciences. Nominations must be submitted by 5pm (CET) 30th September 2014. Self nominations are not accepted.

The award will be given solely on the basis of excellence in research and must include structural data as a key component of the research achievement. The award recognises a clearly defined breakthrough (either in scientific knowledge or technology development) and is not for a lifetime achievement.

Awardees receive an unrestricted grant of €15 000, a personalised certificate and will deliver a lecture at the Instruct Conference in Florence 2015. The Ivano Bertini award is sponsored by Bruker

Eligible nominees: Individual researchers whoes work is conducted within European Member states or Third countries in the last 5 years (1st June 2009 to 31st May 2014).

Nominations: A nomination must be supported by three Instruct members and must include: A completed nomination form (below), CV of the proposed candidate or key members of the nominated research team, a statement from each of the three proposers.

Selection of the Awardee: A committee comprising members of the Instruct Executive Committee, three external scientists from the international Instruct review panel, a member of the sponsor Bruker BioSpin and a member of the Instruct Independent Scientific Advisory Board will be responsible for selecting the awardee from the nominees.

The award will be announced at the Instruct Biennial Biology Meeting 2015

Nominations for the award are now closed

Ivano Bertini

Ivano Bertini was one of a kind. You could always tell when he was near, as his booming voice made the walls tremble and everyone within them take notice. He loved life and his friends with a passion that is rarely seen. Finding he had lung cancer, he fought bravely but passed away on 7 July of this year. In his scientific life, he took biological inorganic chemistry to new heights with the development of powerful new NMR methods to study paramagnetic metalloproteins. And, equally importantly to us and to many others, he and his beautiful wife, Renata, were lovable, caring and fiercely loyal friends.

Ivano will long be remembered for building a world-class laboratory. When starting out in 1989, he had only two NMR spectrometers (200 and 600 MHz), housed in a former church in central Florence that featured sixteenth-century Renaissance frescos on walls with vaulted ceilings. By 1999, there was no room for new spectrometers, so he founded the Center for Magnetic Resonance (CERM; and moved to become the first occupant of the new science campus of the University of Florence. (The CERM was recognized as a center of excellence by the university in 2003.) Today, in a building of about 1,600 square meters, scientists have access to an impressive collection of NMR instruments for solution and solid-state NMR experiments guided by a team of outstanding scientists. A man with seemingly infinite energy, Ivano founded two biotech companies, served as president of the Italian Chemical Society and cofounded the European network on NMR facilities for bio-NMR. His lab has been funded by the European Commission as an NMR infrastructure site since 1994 and as a computational 'e-infrastructure' site since 2007. In 2008, CERM became one of only seven core labs of Instruct.

Nature Structural & Molecular Biology 19, 868–869 (2012)