Colin McVey

Colin McVey

Principal Investigator

Structural VirologyHerpesvirus latency Chromatin modificationprotein-DNA interactions protein-protein interactions

User Biography

My research is focused on gammaherpesvirus viral modulation and the study of proteins encoded by herpesvirus to understand their structural and functional role in viral latency. Viral latency is the ability of a pathogenic virus to lie dormant within a cell. One of the most essential tasks during latency is to maintain the viral episome through cycles of mitotic cell divisions. The focal point of our research is LANA, a multifunctional protein that is critical for the establishment and maintenance of viral latency. My lab combines both biophysical (EMSA, ITC & Thermofluor) and structural methods (BioSAXS & X-ray crystallography) to understand protein interactions involved in viral latency and modulation of its host.

Key Publications

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Scientific Highlights

Qualifications

BSc(Hons) M.Med.Sc DPhil