Diamond Light Source is the UK's national synchrotron facility.
Harwell Science & Innovation Campus
Didcot
OX11 0DE, Harwell
United Kingdom
Diamond Light Source is currently available for remote access only due to COVID-19 restrictions. For information on the availability of specific technologies, view the Technology Availability List or contact support@instruct-eric.eu. Please check here regularly for updates.
The Electron Bio-Imaging Centre (eBIC) provides scientists with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy, for both single particle analysis and cryo-tomography. Currently eBIC houses five Titan Krios microscopes, a Talos Arctica, Glacios, and a Scios and Aquilos cryo-FIB/SEM.
Diamond provides a range of techniques for academic and industrial researchers studying the machines of life. As one of those techniques, Macromolecular Crystallography (MX) reveals the shape and arrangement of biological molecules at atomic resolution, knowledge of which provides a highly accurate insight into function. This can be combined with complementary information from many other techniques available at Diamond alongside lab based investigations to reveal the broader picture of molecular interactions and their effects.
Small Angle X-ray Scattering (SAXS) covers the major disciplines of Biology, Chemistry and Physics delivering structural and dynamic information in nanoscience, mesoscopic architectures, supramolecular structures and nucleation/growth of crystals. SAXS is also proving important in archaeological, environmental and conservation sciences, indicating an ability to span a wide range of scientific disciplines.
Fragment screening through Macromolecular Crystallography at Diamond’s XChem facility at beamline I04-1, supporting 1000+ compound screens