Cryo electron microscopy is a major structural biology method for studying macromolecular complexes and cellular structures in their native states. It can be used to sort out heterogeneous conformations to capture steps in the operation of macromolecular machines. Stable, high-resolution cryo microscopes, direct electron detectors, and automated systems for data collection now allow almost routine biomolecular structure determination at atomic or near-atomic resolution.
The EMBO practical course aims to teach the basic principles and practical aspects of image processing to structural and molecular biologists wishing to determine macromolecular structures by cryo-EM. The course will concentrate on processing of high-resolution image data for both single particle images and tomograms, and is aimed at advanced PhD students and postdocs using cryo-EM for structural analysis.
For more information and to register, click here.