Instruct-ERIC Events

Workshop on real-time cryo-EM image processing with SIMPLE in Oxford

Date: 09-Jan-2018 to 10-Jan-2018

Contact: Hans Elmlund


Workshop on real-time cryo-EM image processing with SIMPLE Oxford, 9-10th January 2018 (designed to allow attendance at the CCP4 workshop immediately after)

Course overview:

SIMPLE (Single-particle IMage Processing Linux Engine) is a program package for cryo-EM image processing, featuring algorithms for all aspects of single-particle image analysis. A recent focus of the SIMPLE development team has been the establishment of a streaming pipeline, allowing real-time image processing of data directly from the microscope with a minimal computing setup.

This workshop is aimed at facility personnel, postdocs and students using single- particle reconstruction as their primary research tool. Processing through 2D, ab initio 3D, heterogeneity analysis, to high resolution refinement will be introduced by each participant independently working through all stages. The new SIMPLE GUI will also be introduced allowing all stages of processing through web browsers on any device.

40 attendees can be accommodated.


The workshop will be the first based at the Central Oxford Structural Microscopy Imaging Centre. This new facility, consisting of a suite of direct electron detector equipped microscopes at 200 and 300kV, brings the cryo-em revolution to scientists based in the Oxford Science Area. A central computing facility associated with the cryo-EM Centre has driven development of the automated real time processing of single particle data to facilitate informed sample selection.


The workshop will cost £150 to include registration, lunch (on both days), coffee breaks. Attendees will need to arrange overnight accommodation in Oxford. Please register interest using the link at top.

Oxford, United Kingdom

Workshop on real-time cryo-EM image processing with SIMPLE in Oxford