Jobs in Structural Biology and Related Fields

A 3 year PhD fellowship is available in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).

The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches.  The projects aim at understanding structure-function relationships with an emphasis on drug discovery.  We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.).  Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo.  Additional projects are available.

The PhD student will also benefit from career development programs offered both at UiO, the Norwegian BioCat initiative as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

Qualification requirements

• Applicants must hold a Master’s degree or equivalent in biochemistry, chemistry, molecular biology or a related.

• Hands-on experience with purification of proteins and assembly of protein complexes.

• Ability to independently perform experiments, analyze and interpret the results.

• Excellent interpersonal/communication skills.

• Fluent oral and written communication skills in English.

• Ability to operate as a team player in a multi-disciplinary environment.

The application must include

• cover letter statement of motivation and research interests

• CV (summarizing education, positions and academic work)

• copies of educational certificates (academic transcripts only)

• a complete list of publications and academic works, with a brief summary of the candidate’s contribution to each paper

• list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)