Our European Projects

In addition to the core activities, Instruct-ERIC is actively working in partnership with others across the Life Sciences field to share expertise and work together on European projects which will benefit the Life Science community more generally. Horizon 2020 (H2020) and Horizon Europe are the EU Research and Innovation Programmes which provide funding in key research areas. Details of our projects are given below, many of which relate to improving research infrastructure, data and training.  

 

Fragment-Screen

From fragments to high affinity binders interfacing integrated structural biology, medicinal chemistry and artificial intelligence

Coordinated by Instruct-ERIC, the Fragment-Screen project aims to develop innovative instrumentation, workflows and experimental and computational methodologies to accelerate the development of new pharmaceuticals using the approach of fragment-based drug discovery (FBDD). It will improve current bottlenecks in signal-to-noise (NMR), automation of data analysis (X-ray), and general applicability of cryo-EM for high-throughput. It will also help make data analysis coherent over different methodological approaches.

February 2023 to January 2026

Total grant: €10 266 290

Read more >>

 

iNEXT-Discovery

Structural biology for translational research and discovery

iNEXT-Discovery aims to enable access to structural biology research infrastructures for all European researchers, and especially non-experts in structural biology. For that reason it brings together a diversity of large research facilities and other groups in a single consortium. Instruct provides the proposal system for the project and the many Instruct-ERIC facilities also offer access to their services through iNEXT-Discovery and contribute to networking and communication activities. Instruct is responsible of the sustainability planning for the activities of the project.

February 2020 to July 2024

Total grant: €9 987 743

Read more >>

 

 

EOSC Future

Advancing European research through Open Science

EOSC Future aims to integrate, consolidate, and connect e-infrastructures, research communities, and initiatives in Open Science to further develop the EOSC Portal, EOSC-Core and EOSC-Exchange of the European Open Science Cloud (EOSC). Instruct-ERIC is involved in two interdisciplinary test science projects within EOSC-Future: Working to enhance access to secure social science data sets using our ARIA software in collaboration with social science research infrastructure CESSDA, and working on improving FAIRness of COVID-19 imaging data i n collaboration with life science research infrastructures EU-OPENSCREEN and Euro-BioImaging.

April 2021 to September 2023

Total grant: €40 877 089

Read more >>

 

BY-COVID

BeYond-COVID

BY-COVID builds and expands upon the successful COVID-19 Data Platform. Rather than focus purely on providing technical solutions to the biological data, BY-COVID will work with partners from a broad range of disciplines, including public health and social sciences, to incorporate a wider range of data. Instruct-ERIC plays a key role in the project, with a number of Instruct partners involved in the FAIRification and interoperability of COVID-related data.

October 2021 to September 2024

Total grant: €12 000 000

Read more >>

 

ISIDORe

Integrated Services for Infectious Disease Outbreak Research

ISIDORe provides research services from structural biology through to clinical trials to support infectious disease epidemic research including SARS-CoV-2. With a special emphasis on addressing the emergent SARS-CoV-2 variants, ISIDORe accelerates the generation of knowledge and tools to tackle epidemic prone pathogens, while avoiding fragmentation and duplication among EU initiatives. Structural biology is a key field in infectiouse disease research, so Instruct will be offering its services to the canSERV community.

February 2022 to January 2025

Total grant: €20 998 624

Read more >>

 

eRImote

Pathway to Improved Resilience and Digital and Remote Access

eRImote considers solutions for digital and remote service provision across RI domains, as well as transferable practices and new developments that will improve accessibility and resilience of RI infrastructures. The aim of eRImote is to create an online information platform with a publicly available data store on best practices and tools for remote provision of RI services. Instruct is heavily involved in all aspects of this project.

June 2022 to November 2024

Total grant: €1 499 997

Read more >>

 

AI4LIFE

Artificial Intelligence for Image Data Analysis in the Life Sciences

AI4LIFE aims to build bridges between the life science community and the machine learning/artificial intelligence community. AI has enormous potential for advancing life sciences (as demonstrated by the Alphafold system in structural biology), however access to the necessary equipment, software and training in AI and machine learning for life science research infrastructures in scarce. AI4LIFE will build an open, accessible, community-driven repository of FAIR pre-trained AI models and develop services to deliver these models to life scientists.

September 2022 to August 2025

Total grant: €4 141 166

Read more >>

 

canSERV

Providing cutting edge cancer research services across Europe

canSERV's mission is to make cutting-edge and customised research services available to the cancer research community EU wide, enable innovative R&D projects and foster precision medicine for patients benefit across Europe. Structural biology is a key field in the pipeline of oncology, so Instruct will be offering its services to the canSERV community. Additionally, the ARIA submission system will be utilised as the central access management software for access provision in canSERV.

September 2022 to August 2025

Total grant: €14 999 939

Read more >>

 

EOSC4Cancer

A European-wide foundation to accelerate Data-driven Cancer Research

EOSC4Cancer will make cancer genomics, imaging, medical, clinical, environmental and socio-economics data accessible, using and enhancing existing federated and interoperable systems for securely identifying, sharing, processing and reusing FAIR cancer data. Instruct represents the structural biology community in this project and provides a connection between EOSC4Cancer and sister project canSERV which is a generator of cancer research data.

September 2022 to February 2025

Total grant: €7 999 876

Read more >>

 

IMAGINE

Next generation imaging for biology across scales

The EU-funded IMAGINE project focuses on developing and integrating major microscopy technologies to enable scale-crossing structural and functional investigation of biological specimens in their natural context. IMAGINE aims at making its new imaging technologies service ready and having them validated as future services by Europe’s Imaging Research Infrastructures, including Instruct-ERIC.

May 2023 to April 2028

Total grant: €9 569 677

Read more >>

 

ERIC Forum 2

Second implementation project for the ERIC Forum

This ERIC Forum continuation project aims to structure the cooperation between ERICs, support the implementation of the ERIC Regulation and ERICs services, and consolidate the integration of the ERICs in the European Research Area by deepening the ERIC Forum’s contribution to research policies. In this new Horizon Europe project Instruct-ERIC will provide leadership in areas of Internationalisation and Communications as well as actively participating in matters of governance, legal framework and administration.

September 2023 to August 2027

Total grant: €2 999 464

Read more >>

 

FHERITALE

The effect of artificial materials on health (direct or through interactions with food and environment) poses several research questions of high impact. FHERITALE aims at providing the European research community with a comprehensive overview of technologies and services, and their readiness and adaptability to address these questions. Instruct will offer experience and expertise on providing services for food and health research, and coordinate results with the wider life science community.

January 2024 to December 2026

Total grant: €2 002 189

Read more >>

 

EU-LAC ResInfra Plus

Following the success of the EU-LAC ResInfra project, EU-LAC ResInfra Plus aims to progress the collaboration between Europe and Latin America, with increased focus on training, exchange of experiences and best practices, and the development of international partnerships. Take a look at Instruct's activities within EU-LAC ResInfra here.