Protein crystallisation at NKI

The Facility has access to a high-throughput macromolecular crystallisation platform. Liquid handling robots are available for preparation of nanoliter crystallisation drops in 96-well format, including a 96-well pipetting robot (CyBi-SELMA) for filling up reservoir wells and a Mosquito for creating nanoliter crystallisation drops. Crystallisation trials can be stored and imaged by two RockImager systems, one at 4 °C and one at 20 °C. When suitable crystals are obtained for x-ray diffraction analysis, the applicant has to collaborate with a crystallography facility. Solving crystal structures is beyond the scope of the facility.

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Instruct Centre

Service/Technology Contacts

  • Anastassis Perrakis login to contact
  • Reinout Raijmakers login to contact
  • Patrick Celie login to contact

User Guide

Please see the NKI protein facility website for more information.