The University of Texas has a postdoctoral position immediately available for a highly motivated individual interested in understanding molecular mechanisms of ubiquitin signaling. Research is focused on the enzymatic machinery responsible for protein ubiquitination, characterization of PROTAC complexes with potential therapeutic value, and structure determination of large protein complexes involved in ubiquitin signaling, particularly those regulating DNA repair. These issues will be addressed using a multidisciplinary approach that includes cryo-EM, X-ray crystallography, and NMR complemented with biochemical/biophysical techniques and cell-based assays.
Candidates should hold a recently obtained PhD in biochemistry, chemistry, or related subject, with demonstrated expertise in cryo-EM, X-ray crystallography, and/or the biochemical analysis of protein ubiquitination. Experience with protein expression in insect and mammalian cells is a plus.
Interested candidates should e-mail a cover letter, CV, and the names of three references to: olsens@uthscsa.edu.
