Integrated structural biology of gene transcription
Structural studies of membrane-embedded protein machines by NMR: From lipid bilayers to cells
Knowing when to cross the mitotic checkpoint
Sp140 and its interaction with chromatin
RNA-protein complexes in RNA metabolism: an integrative structural biology approach
The structure of the influenza virus replication machine: a long time coming but worth waiting for!
Cryo-electron microscopy comes of age: Applications to molecular pharmacology
HIV-1 reverse transcriptase structure and function: drugs by design and recent innovations
TACC3-XAMP215 interaction reveals an asymmetric association promoting spindle microtubule elongation
Impact of structural information in drug discovery
Structural biology towards Cellular Biology: Integrating Biology
Structural Biology and Health: Current Challenges
High resolution Cryo-EM studies at the MRC-LMB: Local setup and examples
Structure determination of functional self-replicating protein filaments by solid-state NMR spectroscopy
“From one seed a whole handful”: homologous proteins as seeds in crystallisation
Nanobody-enabled fragment screening on active-state constrained GPCRs
Synthetic biology meets Structural Biology: New perspectives and opportunities
First research outcomes from Instruct access – proof of principle and future goals
Structural Biology at the European Spallation Source
EATRIS model for translational medicine and innovation in the ERA
Structural Biology Infrastructure provision within ESFRI
Instruct and the other BMS ESFRI Infrastructures in the changing European landscape of Research Infrastructures
Emerging Technologies in Integrative Structural Biology
The Ivano Bertini Award recognises a significant achievement in frontier research that utilises an integrative structural biology approach. The first recipient of the award is Stephen Cusack FRS, Head of EMBL Outstation in Grenoble. His work on the structure of protein-RNA complexes and proteins involved in host-pathogen responses is groundbreaking and exemplifies the power of using integrated technology approaches in research. The Award is the first commemorating Ivano Bertini who developed powerful new methods in NMR and built up a world class Centre for Magnetic Resonance (CERM) in Florence. CERM was in the first group of major Centres in structural biology to form the Core structure of Instruct.
The Award of €15,000 is endowed by Bruker BioSpin which, together with Ivano, developed NMR instrumentation to broaden its application and increase measurement sensitivity.
Dr. Cusack will be receiving the award in the first session of the meeting and will speak about his research in a special Award presentation talk.
The instruct Internship Programme funds research visits of 3-6months duration to Instruct Centres in Europe. The aim is to facilitate valuable collaborations with Instruct research groups. Submit an internship proposal for the programme before the deadline to apply for this opportunity.
Instruct is supporting a limited number of pilot studies proposed by researchers from Instruct member countries. The intent of this support is to help researchers develop external funding projects. Pilot projects may be funded up to a maximum of €20,000. Submit an R&D proposal by the deadline to apply for these funds.